youguessit

Ok, Here is the deal. I just got a new160 degree thermostat. When i had it installed they screwed up and didnt put enough coolant in. When i saw the car overheating when i was hotrodding it i killed it. Now when i floor it and get to 70mph my check engine flashed. I checked my error codes and found that my bank 1 sen1 o2 sensor has low imput. I know that this sensor is a major one for the computer to use for its calculations. I also have a random multiple misfire error code. Can a bad o2 sensor cause misfire? I dont have headers or anything...
THanks