fuel system failure causes boom!
However due to personal experience having the tank sugared on an LS1. I'll venture to say it's going to screw things up over a period of time.
I had this mysterious stumble/missfire on 1 cylinder as soon as I hit 4900 rpm or any large throttle tip-in. O2's were also all over the place. Not the normal switching.
It would only do this under load. Sitting in neutral and revving there were no problems. Swapped and checked coil packs,plugs,wires,springs,pushrods,wiring,various sensors,fuel delivery,etc,etc. Nothing would get rid of it.
After another few days the missfire jumped to another cylinder. It would come and go. Next thing you know I picked up miss-fires on all cylinders and the car barely made it home. After searching around the boards someone pointed me to a thread for someone who had experienced my same problems. His turned out to be sugar in the tank.
So after exhausting all the easy fixes, I pulled the intake and found sticky black slime around the injector holes and all down the intake ports in the heads. Inside the manifold was spotless. The residue was only after the injector ports. Pulled the heads and found excessive carbon build-up in the chambers of the heads and on top of the pistons. By excessive I mean enough build-up to change the effective CR in each cylinder.
I drained/cleaned the tank,cleaned the lines,cleaned all the carbon off the chambers/pistons, and swapped injectors. Re-assembled and fired it up. No more missfires and the car ran like a champ.
Lastly I bought a locking gas cap for both the cars.
As far as finding a locking cap, I got mine from GMpartsdirect.com. If you use the "search" function and type in "locking gas cap" , it should pull up a thread with the PN in there.

