Sticky tires that hook up & a hard launch is what often kills 10-bolt rear ends regardless of power level. Automatics tend to be less brutal on the parts that manual transmissions. Wheel hop can also cause issues.
My six speed manual 99 TA has had 4.10 gears and heads & cam package for over 15 years & 125,000 miles and rear has held together. Car makes 418 wheel horse power. No hard launches are the key to keeping the stock 10 bolt alive for a while. Launching I slip the clutch, no side steps. Other mods like good LCA's to reduce/eliminate wheel hop also help.
Do the mods have fun and start saving for a new rear end like a Hawks 8.8 that can take 1000hp and live with side stepping the clutch at 6000 rpm on sticky tires.