2.73 in a 12 bolt
You won't gain a huge amount of gas mileage unless you do a lot of highway driving. I believe that 3.08s are available and I would not drop below 3.42 if the car is not used as a long distance cruiser.
I have two sets of 2.73's and a single set of 2.56. I normally reserve these for my land speed clients..... but they already got'em done !! So, If your considering that ratio, you will need a gear set and you will need a carrier. Of which I have 2, 2 series Eaton cases left. Talk about a rare case.....
I myself would use a more readily available 3.23. Anything lower and other adjustments need to be made.

