Spark knock
That leads us to the coils. Does your 5.3 have a coil pack, or a coil-on-plug like the LS1. A coil on plug means that each cylinder has it's own separate coil. A coil pack means that you probably have 4 coils running 8 cylinders, I am not familiar with the 5.3.
I had a similar problem on my V-6 that had a 3 coil pack. One of the coils was blown. The symptoms were similar.
If you have a coil pack, I would have the coils tested. If you have 8 individual coils then I don't know.
I am willing to wager a gap is off, plug is not snug in the head, plug wires not connected correctly or possibly a defect in the part.




