Tube question
Screwing the wheels is not required at your power level but many people still do it, your call. If you have never done it I would get someone with experience to assist you. It would suck to screw-up a good set of wheels. If you have a set of junk wheels laying around I would practice on them.
Good luck
I'm not sure what you mean by real world experience. Yes I have never run these tire but I have been active in racing for over 40 years.

