chamber design and piston shape both play a huge roll in flame travel(or propagation) by allowing the mixture to travel freely in the cylinder and completely fill the quench area when it's time to light off. If you have a large dome on the pistons and a head design that's not at %110 you have a very good chance that the mix will light off all on one side(or close to it) of the piston. The chamber works in conjuction with the piston design, port configuration, camshaf, etc in order to keep the mixture mixed and swirling as efficiently as possible in order to allow a complete lightoff. If it ligts on one sideor the other you will build hot-spots that will cause detonation and/or with all the loading being on one side or the other the piston will have a harder time moving in the bore because the explosion is tryin to send it sideways. This is a HUGE HP robber that many back-yard builders fail to ever see but it's there. For this very reason I have ALWAYS preferred to use a flat-top design piston with a very efficient set of heads. Add to that the hottest ignition system you can get and it MIGHT run. I like all the fire from the plugs I can get. A big compression motor can qute literally blow the spark out in a cylinder if the ignition isn't up to the job. I also like to run a big plug gap as well so the spark has the best possible chance to ignite all that junk I just threw in the hole....... oops, you asked about chamber design and I got off on another page...sorry. Yes, chamber design has a HUGE affect on flame travel since that along with camshaft selection and ignition are the brains of the motor........ wow, that was too simple, sorry!!