Car randomly falls on it's face while under load!
The same thing is happening to my car from 3800-4k RPM . It makes good power and then it falls flat on its face on all 3 dyno pulls.
Initial hunch I would think it would be the coils. Could also be the mass air flow meter or even a collapsing lifter leading to valve issues.
Run the compression test to make sure
My original PCM never threw codes for bad MAF, TPS or IAC valve. Also, when my Crank Shaft Position sensor was killing my engine while I was dirving down the street.....nothing, no codes. A real pain in the ***. Some PCM's show everything.
I've unplugged my MAF before trying to find a problem, I left it unplugged for like 3 months. Tuners told me that my PCM reverted to a SD mode. The engine ran great, down low, mid and top end. No need for the MAF...and gas mileage was the same. So give that a try.....
Also, scan it for codes. You might not get the SES light, but a code could be there.
I'd be leaning toward a PCM or electrical issue. A mechanical issue seems like it would never go away.....and you say it runs great at times, right?
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A failing Crank Shaft Position sensor will cause your issues too. Its a very random thing when they're failing.
Something as simple as a spark plug wire touching or bouncing up against the manifold piping will too.
Maybe even a cracked ceramic part of a spark plug.
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Try the Crank sensor.....it take 5 minutes to replace. You can return it if it doesn't help.
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A friend is telling me that since I went a very long time between plug changes it could have screwed up the coils. I'm doubtful of this because according to GM it's designed to go 100K miles between plug changes anyways. Granted I would never attempt that but just saying lol. I think I will try and track down a genuine GM part for the crank sensor instead of some advanced auto crap. 

