400ci
Only reason I see for staying with a short stroke is for high revving road track motors. A street/strip car is not one that really needs to see 8000rpm for extended periods of time, so you'd want as much stroke as possible for more torque under the curve which is great for a street car and one that needs to accelerate quick.
For a purely top end screaming engine yes your setup would be great.
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I'd also use LS7 heads on something with that much bore.
Preferably, I'd do a 4.185" bore with 4.125" stroke and spin the 454 to 7500 all day with some aftermarket LS7 heads and aim for 700rwhp all motor.
And like Jake said, that much bore will allow for some nice heads but will be dragged down by the overall smallish displacement. What's the point of a 450+ cfm flowing head with 2.200" intake valves when all it has to do is feed a measily 400 cubic inches?
Get a 4+ stroke in there and you'll still be able to rev to 7200rpm but have a much meatier torque curve before that. Stock stroke on such a beastly motor is mainly for those limited to a certain displacement size.
Let's make a few calculations at the OP's intended 7200 rpms, or 120 revolutions/sec.
All 8 pistons travel 289.76 linear feet of distance each second in a 3.622" stroke combo.
@ 4.000" that distance jumps to 320 feet/sec.
4.125 equals 330
I'm thinking the OP's combo would make less peak but more average torque than a 4" X4"
engine (all other parts being equal). Smaller NA motors for lb/in classes always seem to
make less overall power but are more efficient because of the breath ability and reduced
piston speed.
This helps to explain why NASCAR engines (4.185 X 3.25) survive @ 9000 plus rpms as
the piston speed is similar to a 3.75" @ 7800 or 4" @ 7300.
A set of floor epoxied (smaller CSA) Frankenstein LS7 heads would be badass on this OP
combo, however the Ex. ported LS3 heads is still a pretty darn good idea if the right bump
stick is used.
But as said before, a different setup with a longer stroke and even smaller bore will make more torque and power. A proper setup 416 will kill it in torque and snappiness and make more power up top to boot.






