ClifZ28

I was looking at these heads in the latest issue of Hot Rod. I was just wondering if the bolt hole in the port floor, and the access hole with a plug in the port roof will hurt flow characteristics on a N/A motor, or does it not really matter? Would it be better to not have these "holes" on a N/A motor?

What would be the smallest bore size that would be compatible with these big valve heads. I think the Intake Valve is 2.20".

Thanks