When I upgraded injectors from 26's to 28's I just made the number the same across the board in my IFR tables. All cells are the same.

If I want to start tuning the VE table is that going to be a problem? Should I put them back to what they were for the 26's and do the formula and start from there?

 

I would suggest using the formula. The variation by cell accounts for the difference in pressure/vacuum.