O2 sensor ? Necessary or not?
then no. If you've got unrealistic stuff in the tune (a
stock tune becomes unrealistic w/ mods) then trimming
may be needed to get it to run clean and (relatively)
tight.
Some people run open loop full time, on purpose. It's
not a bad way to go if you do it well and maintain it.
Of course the Smog Taliban have a different opinion.

If you run open-loop with MAF that should adjust enougth for day to day changes in the weather. Works fine for me, been in OL-MAF for about 2 months now, fueling looks constant.






