Big problem?!
Honestly, I'd be looking for a short somewhere. Ignition, IIRC, is referenced to the key being on and not necessarily the starter being on. You'll need a wiring diagram to see exactly what that fuse feeds, then disconnect everything on that circuit and reconnect them one at a time until it pops again. That's how I'd look for the issue.
If you look in the fuse and relay panel in the engine bay, there should be a bunch of pink wires. They power the injectors, sensors, etc. one of them is shorting out.
Start by looking for damaged pieces of the harness and seeing if any pink wires have exposed copper.
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I had just dropped the starter yesterday to fix a loose wire and put it back together and it ran fine until this morning when it did that
Not sure about how it is on LS1 engines when it comes to measure the distance between flywheel and starter gear.....









