Never ending P0300
Misfire on only 4&7 means the fuel and ignition is generally ok which rules out most of the engine controls and narrows it down to a couple of cylinder specific problems.
First you pull those plugs and look for damage or fowling or any other signs of the problem. If they're soaked in full for instance it'll narrow down the issue.
You swapped coils and wires but the problem stays with those cylinders. Which means that either the wiring harness leading to those coils is bad (faulty connector possibly) or the ignition is fine and the problem is elsewhere.
You swapped injectors and the problem stayed with those cylinders which rules out clogged or bad injectors. It could be an issue in the wiring harness leading to those injectors (faulty connector possibly)
If the problem stays with the cylinders after swapping coils/wires, plugs and injectors then it's a valvetrain/piston issue (your compression check seems to rule that out) or it's time to open up the harness and look for chafed wires.
I could pull the main harness and physically check the wires and connectors. They all ohmed good, and I swapped the coil harnesses with no change. I had someone else mention either alternator issues or maybe crank position relearn needs to be done. My engine and ECU are from different vehicles, so I could potentially see the crank sensor relearn, although I’m not throwing any of those codes.
Usually with a 300 you have a common source issue. Bad fuel, low pressure, bad MAF or MAP. In other words not usually a single cylinder issue like A plug or A wire.
If it stumbles on tip in it's likely has a fueling issue. May be a timing issue as well.
If all cylinders are low on compression, I would suspect cam timing may be off a tick.
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Time for a fuel psi check.
Data logs?








