Cylinder 6 Misfire
Two free checks you can do to narrow it down:
1. Swap the coil harnesses, keeping the purple wire opposite, as in #1 and #8 cylinder. The order is the same. On bank two, the purple starts at the back, bank one it's in the front.
2. Switch your coil pack out to another location.
If it's not the harness, it doesn't mean it couldn't be elsewhere in the engine harness. Check your grounds, and check your signal and power wires to the PCM. The spark is fired by grounding the circuit. So at all other times you should see an open circuit. Also, the injectors fire before the coils do. Also easy to check with a noid light, if all the wiring checks out, seals, coils, etc.
It's pretty hard to think of more things at the moment to check, but start with the free checks, and the easier ones to do. Personally I would have already had the harnesses swapped. If that doesn't change it, then the coil, and then after that, I'd start digging deeper.
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As Darth stated I would start with a compression test, then a leak down. I'd pull the valve cover off, inspect the springs, rocker arms and pushrods.
Depending on what scanner you have you can check the misfire counter and see how much that cylinder is actually misfiring. It has to hit a certain number of misfires before it will actually kick a p0306 dtc. Lets say the threshold is 1000 misfires within a certain amount of time and it misses 999, it won't kick the CEL on.
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